Biospace β Imager

ultrafast, real-time quantitative autoradiography


 
     
     
 


Tritium detection 500 times faster than film :

Tritium is a reliable beta emitter for measurement of biological samples. The problem is, detection is slow. Traditional film and phosphor imaging methods can take weeks to complete. But now, there is a better way to meet high throughput needs: β Imager cuts tritium imaging time from weeks to hours.


4 week imaging plate acquisition (left) of rat brain sections using a 3H labeled probe compared to a 5 hour β imager acquisition (right).
Imaging plate: 4 weeks β imager: 5 hours

A patented imaging system with unsurpassed sensitivity

  • detection threshold for tritium is 0.007 cpm/mm2 : very low radioactive levels can be detected
  • real-time imaging avoids under or over exposure and shows acquired image status at any time
  • direct beta counting makes results absolutely reproducible, minimizing repeat experiments
  • 60 ìm spatial resolution is reachable with an optical zoom
  • an exclusive patent allows simultaneous imaging and discrimination of multiple emitters
  • precise quantitation can be performed even at very short time

A versatile technology

  • ideal for tritium detection in samples up to 20 cm by 25 cm
  • detects all other usual beta emitting isotopes (14C, 32P, 35S, 33P, 125I)
  • detects electrons associated with gamma isotopes with high resolution and speed (123I, 131I, 99mTc, 201Tl, 111In, ...)
  • detects positrons associated with PET isotopes

A wide range of applications

  • receptors binding
  • whole body section
  • tissue sections on glass slides
  • any tissue sections
  • TLC plates
  • electrophoresis gels or membranes
  • hybridization membranes
  • ex vivo imaging after in vivo sessions (µSPECT, µPET)
   
 

Quantitative dual labelling on slides for full field of view Qualitative dual labelling on membranes for full field of view


3H
14C
     
 


3H labelled section of human brain. Obtained in 4 hours, vs 4 days with phosphor screens and 4 weeks with film.